Phthalate exposure and health outcomes
نویسندگان
چکیده
Phthalates are used in commercial products as softners of plastics, solvents in perfumes and additives to hair sprays, lubricants and insect repellents. The wide spread use of phthalate results in multiple human exposure routes i.e., ingestion, inhalation and dermal exposure. In the present review, a detailed account of respiratory toxicity, phthaltes is high given their use in a vast range of consumable products and because they are not covalently bound to the other chemicals in the formulations. After exposure, phthalates are rapidly hydrolyzed to their respective monoesters which can be further biotransformed to Review Article S. K. Rastogi, C. Kesavachandran*, Farzana Mahdi, Amit Pandey Era’s Lucknow Medical College and Hospital, Lucknow, *Epidemiology Section, Industrial Toxicology reproductive toxicity, developmental toxicity, endocrine oxidative metabolites. Research Centre disruptors and genotoxicity of human exposure to (CSIR), Lucknow, India phthalate is mentioned in detail. The wide spread use of phthalates results in multiple human exposure For correspondence:
منابع مشابه
Phthalate exposure and children's health.
PURPOSE OF REVIEW Phthalates are multifunctional chemicals used in personal care products, medications, and plastics. We reviewed the epidemiological literature examining the relationship between early life phthalate exposure and pediatric health outcomes. RECENT FINDINGS Five studies from Asia, Europe, and the United States suggest that childhood exposure to di-2-ethylhexyl phthalate (DEHP) ...
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